jonathanJonathan Shestack is a celebrated Hollywood producer  who founded  CAN (Cure Autism Now) in 1995 with his with wife,  Portia Iversen (parents of their autistic son, Dov). In its 12-year history, CAN contributed more than $39 million to autism research and education programs, established a federal advocacy initiative which led passage of the Children's Health Act of 2000 and Combating Autism Act of 2006, and raised the profile of autism through celebrity outreach and grassroots initiatives. 

Jonathan Shestack joined the board and executive committee of Autism Speaks in February 2007, following the merger with Cure Autism Now (CAN). In 2002, Shestack was appointed as one of three public members to the NIH Interagency Autism Coordinating Committee and serves on the Subcommittee on Screening and Early Diagnosis.Shestack also serves on the Internal Citizens Oversight Committee of the California Institute for Regenerative Medicine and two bio-ethics task forces--a Department of Energy group on issues of ethics and gene patenting and the Stanford University Center on Integrating Ethics and Genetic Research. Shestack also founded CAN's flagship program, the Autism Genetic Resource Exchange (AGRE).

Shestack is a film producer based at New Line.  He was president of production of Artisan Entertainment and executive vice president of Beacon Entertainment where he produced " Air Force One," "Family Man" and "Bring It On."